PICALM
phosphatidylinositol binding clathrin assembly protein
Sinonimi:
CALM, CLTH, LAP
Specie:
Human PICALM (8301), Mouse Picalm (233489), Rat Picalm (89816), chicken PICALM (425991), dog PICALM (476780), Horse PICALM (100050701), domestic cat PICALM (101094948), domestic guinea pig Picalm (100729067), naked mole-rat Picalm (101706016), cow PICALM (513579)
ID UniProtKB:
ID gene:
- Human(8301) Summary: This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10;11)(p13;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
- Mouse(233489) phosphatidylinositol binding clathrin assembly protein
- Rat(89816) phosphatidylinositol binding clathrin assembly protein
- chicken(425991) phosphatidylinositol binding clathrin assembly protein
- dog(476780) phosphatidylinositol binding clathrin assembly protein
- Horse(100050701) phosphatidylinositol binding clathrin assembly protein
- domestic cat(101094948) phosphatidylinositol binding clathrin assembly protein
- domestic guinea pig(100729067) phosphatidylinositol binding clathrin assembly protein
- naked mole-rat(101706016) phosphatidylinositol binding clathrin assembly protein
- cow(513579) phosphatidylinositol binding clathrin assembly protein
- sheep(101103193) phosphatidylinositol binding clathrin assembly protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PICALM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PICALM antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Anti-PICALM, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-PICALM Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse
Applicazione
western blot