PHGDH
phosphoglycerate dehydrogenase
Synonyms:
3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA
Species:
Human PHGDH (26227), Mouse Phgdh (236539), Rat Phgdh (58835), Zebrafish phgdh (321928), chicken PHGDH (424381), Horse PHGDH (100059940), domestic cat PHGDH (101088505), naked mole-rat Phgdh (101712402), domestic guinea pig Phgdh (100726801), cow PHGDH (505103)
UniProtKB ID:
Gene ID:
- Human(26227) Summary: This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
- Mouse(236539) 3-phosphoglycerate dehydrogenase
- Rat(58835) phosphoglycerate dehydrogenase
- Zebrafish(321928) phosphoglycerate dehydrogenase
- chicken(424381) phosphoglycerate dehydrogenase
- Horse(100059940) phosphoglycerate dehydrogenase
- domestic cat(101088505) phosphoglycerate dehydrogenase
- naked mole-rat(101712402) phosphoglycerate dehydrogenase
- domestic guinea pig(100726801) phosphoglycerate dehydrogenase
- cow(505103) phosphoglycerate dehydrogenase
- sheep(101111328) phosphoglycerate dehydrogenase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-3-PGDH Antibody, clone TK-08 13A8, clone TK-08 13A8, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-PHGDH antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0555, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PHGDH antibody produced in mouse, clone 4A3-1D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-PHGDH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-3-PGDH Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
chimpanzee, human, mouse, porcine
Application
immunohistochemistry
western blot
western blot
esiRNA
Product Number
Description
Species