PDHB
pyruvate dehydrogenase (lipoamide) beta
Synonyms:
PDHBD, PDHE1-B, PHE1B
Species:
Human PDHB (5162), Mouse Pdhb (68263), Rat Pdhb (289950), cow PDHB (613610), sheep PDHB (101121975), domestic guinea pig Pdhb (100733476), naked mole-rat Pdhb (101714134), Zebrafish pdhb (406428), Horse PDHB (100050581), domestic cat PDHB (101100374) ...More
UniProtKB ID:
Gene ID:
- Human(5162) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
- Mouse(68263) pyruvate dehydrogenase (lipoamide) beta
- Rat(289950) pyruvate dehydrogenase (lipoamide) beta
- cow(613610) pyruvate dehydrogenase (lipoamide) beta
- sheep(101121975) pyruvate dehydrogenase (lipoamide) beta
- domestic guinea pig(100733476) pyruvate dehydrogenase (lipoamide) beta
- naked mole-rat(101714134) pyruvate dehydrogenase (lipoamide) beta
- Zebrafish(406428) pyruvate dehydrogenase (lipoamide) beta
- Horse(100050581) pyruvate dehydrogenase (lipoamide) beta
- domestic cat(101100374) pyruvate dehydrogenase (lipoamide) beta
- dog(476574) pyruvate dehydrogenase (lipoamide) beta
- chicken(416066) pyruvate dehydrogenase (lipoamide) beta
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PDHB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-PDHB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-PDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PDHB antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Kits
Product Number
Description
Species
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Species
rat, mouse, human