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Merck

PCSK6

proprotein convertase subtilisin/kexin type 6

Synonyms:
PACE4, SPC4
Species:
UniProtKB ID:
Gene ID:
  • Human(5046) Summary: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(18553) proprotein convertase subtilisin/kexin type 6
  • Rat(25507) proprotein convertase subtilisin/kexin type 6
  • chicken(395454) proprotein convertase subtilisin/kexin type 6
  • dog(488703) proprotein convertase subtilisin/kexin type 6
  • Horse(100057677) proprotein convertase subtilisin/kexin type 6
  • domestic cat(101083941) proprotein convertase subtilisin/kexin type 6
  • domestic guinea pig(100716755) proprotein convertase subtilisin/kexin type 6
  • naked mole-rat(101721857) proprotein convertase subtilisin/kexin type 6
  • Domestic Rabbit(100347173) proprotein convertase subtilisin/kexin type 6
  • cow(524684) proprotein convertase subtilisin/kexin type 6
  • sheep(101112091) proprotein convertase subtilisin/kexin type 6

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PCSK6, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-PCSK6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PCSK6,
Species
human
MISSION® esiRNA, targeting mouse Pcsk6,
Species
mouse
MISSION® esiRNA, targeting human PCSK6 (2),
Species
human