PCDHA12
protocadherin alpha 12
Synonyms:
PCDH-ALPHA12
Species:
Human PCDHA12 (56137), Mouse Pcdha12 (192164), Rat Pcdha12 (116779), sheep PCDHA12 (101122858), chicken PCDHA12 (497222), domestic cat PCDHA12 (101093237), dog PCDHA12 (607297)
UniProtKB ID:
Gene ID:
- Human(56137) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- Mouse(192164) protocadherin alpha 12
- Rat(116779) protocadherin alpha 12
- sheep(101122858) protocadherin alpha 12
- chicken(497222) protocadherin alpha 12
- domestic cat(101093237) protocadherin alpha 12
- dog(607297) protocadherin alpha 12
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PCDHA12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-PCDHA12 antibody produced in mouse, clone 1D3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA