PCBP1
poly(rC) binding protein 1
Synonyms:
HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
Species:
Human PCBP1 (5093), Mouse Pcbp1 (23983), Rat Pcbp1 (500242), Horse PCBP1 (100050579), dog PCBP1 (481417), domestic cat PCBP1 (101095571), cow PCBP1 (509917), sheep PCBP1 (101106505), domestic guinea pig Pcbp1 (100726474), naked mole-rat Pcbp1 (101726771)
UniProtKB ID:
Gene ID:
- Human(5093) Summary: This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008]
- Mouse(23983) poly(rC) binding protein 1
- Rat(500242) poly(rC) binding protein 1
- Horse(100050579) poly(rC) binding protein 1
- dog(481417) poly(rC) binding protein 1
- domestic cat(101095571) poly(rC) binding protein 1
- cow(509917) poly(rC) binding protein 1
- sheep(101106505) poly(rC) binding protein 1
- domestic guinea pig(100726474) poly(rC) binding protein 1
- naked mole-rat(101726771) poly(rC) binding protein 1
- Domestic Rabbit(100008848) poly(rC) binding protein 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-hnRNP E1/PCBP1 Antibody, clone 7M1K0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-PCBP1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-PCBP1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-PCBP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-PCBP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot