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PARP2

poly (ADP-ribose) polymerase 2

Synonyms:
ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Species:
Human PARP2 (10038), Mouse Parp2 (11546), Rat Parp2 (290027), Zebrafish parp2 (100007906), cow PARP2 (505828), Horse PARP2 (100072572), domestic cat PARP2 (101090944), dog PARP2 (475392), domestic guinea pig Parp2 (100720452), sheep PARP2 (101118027)
UniProtKB ID:
Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8
Gene ID:
  • Human(10038) Summary: This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
  • Mouse(11546) poly (ADP-ribose) polymerase family, member 2
  • Rat(290027) poly (ADP-ribose) polymerase 2
  • Zebrafish(100007906) poly (ADP-ribose) polymerase family, member 2
  • cow(505828) poly (ADP-ribose) polymerase 2
  • Horse(100072572) poly (ADP-ribose) polymerase 2
  • domestic cat(101090944) poly (ADP-ribose) polymerase 2
  • dog(475392) poly (ADP-ribose) polymerase 2
  • domestic guinea pig(100720452) poly (ADP-ribose) polymerase 2
  • sheep(101118027) poly (ADP-ribose) polymerase 2

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA052003
Anti-PARP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB5702581
Anti-PARP2 Antibody, clone 6G5U7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
SAB1304746
ANTI-PARP2 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot
SAB2108489
Anti-PARP2, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
P248
Monoclonal Anti-PARP antibody produced in mouse, clone C-2-10, ascites fluid,
Species Reactivity
hamster, mouse, primate, rat
Application
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot

Cell Lines

Product Number
Description
Species
CLLS1066
MCF10A CELLS PARP2 (-/-), ,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
N7287
NU-1025, ≥97% (HPLC), solid,
Species
mouse
H57807
4-Hydroxyquinazoline, 98%,
Species
mouse

Proteins

Product Number
Description
Species
SRP0193
PARP2 Active human, recombinant, expressed in baculovirus infected insect cells, ≥60% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EHU025371
MISSION® esiRNA, targeting human PARP2,
Species
human
EMU020061
MISSION® esiRNA, targeting mouse Parp2,
Species
mouse