PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
Synonyms:
PAK5
Species:
Human PAK6 (56924), Mouse Pak6 (214230), Rat Pak6 (296078), chicken PAK6 (428837), dog PAK6 (487490), domestic cat PAK6 (101091201), cow PAK6 (539224), Horse PAK6 (100071463), Goat PAK6 (100860973), sheep PAK6 (101112573) ...More
UniProtKB ID:
Gene ID:
- Human(56924) Summary: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
- Mouse(214230) p21 protein (Cdc42/Rac)-activated kinase 6
- Rat(296078) p21 protein (Cdc42/Rac)-activated kinase 6
- chicken(428837) p21 protein (Cdc42/Rac)-activated kinase 6
- dog(487490) p21 protein (Cdc42/Rac)-activated kinase 6
- domestic cat(101091201) p21 protein (Cdc42/Rac)-activated kinase 6
- cow(539224) p21 protein (Cdc42/Rac)-activated kinase 6
- Horse(100071463) p21 protein (Cdc42/Rac)-activated kinase 6
- Goat(100860973) p21 protein (Cdc42/Rac)-activated kinase 6
- sheep(101112573) p21 protein (Cdc42/Rac)-activated kinase 6
- Domestic Rabbit(100348921) p21 protein (Cdc42/Rac)-activated kinase 6
- naked mole-rat(101706200) p21 protein (Cdc42/Rac)-activated kinase 6
- domestic guinea pig(100713585) p21 protein (Cdc42/Rac)-activated kinase 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PAK6 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit
Application
western blot
Anti-phospho-PAK5/6 (pSer602/560) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-phospho-PAK5/6 (pSer602/Ser560) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Proteins
Product Number
Description
Species
PAK6, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
esiRNA
Product Number
Description
Species