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PACS1

phosphofurin acidic cluster sorting protein 1

Synonyms:
MRD17
Species:
UniProtKB ID:
Gene ID:
  • Human(55690) Summary: This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]
  • Mouse(107975) phosphofurin acidic cluster sorting protein 1
  • Rat(171444) phosphofurin acidic cluster sorting protein 1
  • naked mole-rat(101701857) phosphofurin acidic cluster sorting protein 1
  • domestic guinea pig(100727661) phosphofurin acidic cluster sorting protein 1
  • sheep(101104443) phosphofurin acidic cluster sorting protein 1
  • chicken(421254) phosphofurin acidic cluster sorting protein 1
  • cow(514313) phosphofurin acidic cluster sorting protein 1
  • domestic cat(101098825) phosphofurin acidic cluster sorting protein 1
  • dog(483716) phosphofurin acidic cluster sorting protein 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PACS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-PACS1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Pacs1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PACS1,
Species
human