OTUD5
OTU domain containing 5
Synonyms:
DUBA
Species:
Human OTUD5 (55593), Mouse Otud5 (54644), Rat Otud5 (363452), cow OTUD5 (539145), domestic cat OTUD5 (101098283), dog OTUD5 (480911), sheep OTUD5 (101106912), naked mole-rat Otud5 (101712863), domestic guinea pig Otud5 (100732793)
UniProtKB ID:
Gene ID:
- Human(55593) Summary: This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
- Mouse(54644) OTU domain containing 5
- Rat(363452) OTU domain containing 5
- cow(539145) OTU domain containing 5
- domestic cat(101098283) OTU domain containing 5
- dog(480911) OTU domain containing 5
- sheep(101106912) OTU domain containing 5
- naked mole-rat(101712863) OTU domain containing 5
- domestic guinea pig(100732793) OTU domain containing 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OTUD5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-OTUD5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry