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Merck

OTUB1

OTU domain, ubiquitin aldehyde binding 1

Sinónimos:
OTB1, OTU1
Especie:
ID UniProtKB:
ID del gen:
  • Human(55611) Summary: The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(107260) OTU domain, ubiquitin aldehyde binding 1
  • Rat(293705) OTU domain, ubiquitin aldehyde binding 1
  • chicken(777320) OTU domain, ubiquitin aldehyde binding 1
  • domestic cat(101096843) OTU domain, ubiquitin aldehyde binding 1
  • cow(540984) OTU domain, ubiquitin aldehyde binding 1
  • dog(611228) OTU domain, ubiquitin aldehyde binding 1
  • domestic guinea pig(100714472) OTU domain, ubiquitin aldehyde binding 1
  • naked mole-rat(101706271) OTU domain, ubiquitin aldehyde binding 1
  • sheep(101122063) OTU domain, ubiquitin aldehyde binding 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-OTUB1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-OTUB1 (57-70) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-OTUB1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
mouse
Aplicación
ELISA
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human OTUB1,
Especie
human
MISSION® esiRNA, targeting mouse Otub1,
Especie
mouse