OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Synonyms:
AKGDH, E1k, OGDC
Species:
Human OGDH (4967), Mouse Ogdh (18293), Rat Ogdh (360975), chicken OGDH (426429), cow OGDH (534599), domestic cat OGDH (101096048), dog OGDH (475499), domestic guinea pig Ogdh (100724083), naked mole-rat Ogdh (101716205), Domestic Rabbit OGDH (100359048)
UniProtKB ID:
Gene ID:
- Human(4967) Summary: This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
- Mouse(18293) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- Rat(360975) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- chicken(426429) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- cow(534599) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- domestic cat(101096048) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- dog(475499) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- domestic guinea pig(100724083) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- naked mole-rat(101716205) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- Domestic Rabbit(100359048) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
- sheep(101115360) oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OGDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OGDH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-OGDH antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, horse, human
Application
western blot