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Merck

OAS1

2'-5'-oligoadenylate synthetase 1, 40/46kDa

別名:
IFI-4, OIAS, OIASI
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4938) Summary: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • domestic guinea pig(100721851) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • naked mole-rat(101699903) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • sheep(101110181) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • sheep(100294650) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • dog(608778) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • Horse(100034147) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
  • domestic cat(101087875) 2'-5'-oligoadenylate synthetase 1, 40/46kDa

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-OAS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-OAS1 Antibody, clone 1D11.1, clone 1D11.1, from mouse,
交差性
human
アプリケーション
western blot
Anti-OAS1 Antibody, clone 1N2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
ELISA
affinity binding assay

immunocytochemistry

immunohistochemistry

western blot
抗OAS1抗体(ab3) ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-OAS1 antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human OAS1,
Species
human
MISSION® esiRNA, targeting mouse Oas1e,
Species
mouse