NR1H2
nuclear receptor subfamily 1, group H, member 2
Synonyms:
LXR-b, LXRB, NER, NER-I, RIP15, UNR
Species:
Human NR1H2 (7376), Mouse Nr1h2 (22260), Rat Nr1h2 (58851), domestic cat NR1H2 (101087367), cow NR1H2 (509622), Horse NR1H2 (100052399), dog NR1H2 (610057), sheep NR1H2 (101111571), naked mole-rat Nr1h2 (101700273), Domestic Rabbit NR1H2 (100462688)
UniProtKB ID:
Gene ID:
- Human(7376) Summary: The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]
- Mouse(22260) nuclear receptor subfamily 1, group H, member 2
- Rat(58851) nuclear receptor subfamily 1, group H, member 2
- domestic cat(101087367) nuclear receptor subfamily 1, group H, member 2
- cow(509622) nuclear receptor subfamily 1, group H, member 2
- Horse(100052399) nuclear receptor subfamily 1, group H, member 2
- dog(610057) nuclear receptor subfamily 1, group H, member 2
- sheep(101111571) nuclear receptor subfamily 1, group H, member 2
- naked mole-rat(101700273) nuclear receptor subfamily 1, group H, member 2
- Domestic Rabbit(100462688) nuclear receptor subfamily 1, group H, member 2
- domestic guinea pig(100719951) nuclear receptor subfamily 1, group H, member 2
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Small Molecule - Agonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-LXR-B antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-NR1H2 antibody produced in mouse, clone 1E1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-NR1H2 antibody produced in mouse, clone 2H2-H3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-NR1H2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NR1H2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species
Proteins
Product Number
Description
Species
LXR, β isoform, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
LXR β isoform, ligand binding domain (211-461), GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
LXR β-ligand binding domain (211-461) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human