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Merck

NPM1

nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Synonyms:
B23, NPM
Species:
UniProtKB ID:
Gene ID:
  • Human(4869) Summary: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
  • Mouse(18148) nucleophosmin 1
  • Rat(25498) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • chicken(396203) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • domestic cat(101094904) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • cow(614028) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • dog(479292) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • naked mole-rat(101701761) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • Domestic Rabbit(100328693) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • domestic guinea pig(101788218) nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • sheep(101104783) nucleophosmin (nucleolar phosphoprotein B23, numatrin)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NPM1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, goat, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-NPM1 antibody produced in mouse, clone 3B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-NPM1 antibody produced in mouse, clone 1B11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-NPM1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
Anti-phospho-NPM (pThr199) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NPM1,
Species
human
MISSION® esiRNA, targeting mouse Npm1,
Species
mouse