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Merck

NOD2

nucleotide-binding oligomerization domain containing 2

Sinonimi:
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
Specie:
Human NOD2 (64127), Mouse Nod2 (257632), Rat Nod2 (291912), domestic guinea pig Nod2 (100727812), Domestic Rabbit NOD2 (100356594), naked mole-rat Nod2 (101709371), sheep NOD2 (780465), Zebrafish nod2 (777696), cow NOD2 (444867), domestic cat NOD2 (101096863)
ID UniProtKB:
Q9HC29, E2JEQ6, Q96RH5, Q96RH6, Q96RH8
ID gene:
  • Human(64127) Summary: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(257632) nucleotide-binding oligomerization domain containing 2
  • Rat(291912) nucleotide-binding oligomerization domain containing 2
  • domestic guinea pig(100727812) nucleotide-binding oligomerization domain containing 2
  • Domestic Rabbit(100356594) nucleotide-binding oligomerization domain containing 2
  • naked mole-rat(101709371) nucleotide-binding oligomerization domain containing 2
  • sheep(780465) nucleotide-binding oligomerization domain containing 2
  • Zebrafish(777696) nucleotide-binding oligomerization domain containing 2
  • cow(444867) nucleotide-binding oligomerization domain containing 2
  • domestic cat(101096863) nucleotide-binding oligomerization domain containing 2
  • dog(487286) nucleotide-binding oligomerization domain containing 2

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
HPA041985
Anti-NOD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
04-145
Anti-NOD2 Antibody, clone 2D9, clone 2D9, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot
PRS2513
Anti-NOD2 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunocytochemistry
immunofluorescence
western blot

esiRNA

N° Catalogo
Descrizione
Specie
EMU090561
MISSION® esiRNA, targeting mouse Nod2,
Specie
mouse
EHU033731
MISSION® esiRNA, targeting human NOD2,
Specie
human