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Merck

NOD2

nucleotide-binding oligomerization domain containing 2

Synonyms:
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
Species:
Human NOD2 (64127), Mouse Nod2 (257632), Rat Nod2 (291912), domestic guinea pig Nod2 (100727812), Domestic Rabbit NOD2 (100356594), naked mole-rat Nod2 (101709371), sheep NOD2 (780465), Zebrafish nod2 (777696), cow NOD2 (444867), domestic cat NOD2 (101096863)
UniProtKB ID:
Q9HC29, E2JEQ6, Q96RH5, Q96RH6, Q96RH8
Gene ID:
  • Human(64127) Summary: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(257632) nucleotide-binding oligomerization domain containing 2
  • Rat(291912) nucleotide-binding oligomerization domain containing 2
  • domestic guinea pig(100727812) nucleotide-binding oligomerization domain containing 2
  • Domestic Rabbit(100356594) nucleotide-binding oligomerization domain containing 2
  • naked mole-rat(101709371) nucleotide-binding oligomerization domain containing 2
  • sheep(780465) nucleotide-binding oligomerization domain containing 2
  • Zebrafish(777696) nucleotide-binding oligomerization domain containing 2
  • cow(444867) nucleotide-binding oligomerization domain containing 2
  • domestic cat(101096863) nucleotide-binding oligomerization domain containing 2
  • dog(487286) nucleotide-binding oligomerization domain containing 2

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1409648
Anti-NOD2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
04-145
Anti-NOD2 Antibody, clone 2D9, clone 2D9, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
PRS2513
Anti-NOD2 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunofluorescence
western blot