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NLRP12

NLR family, pyrin domain containing 12

Synonyms:
CLR19.3, FCAS2, NALP12, PAN6, PYPAF7, RNO, RNO2
Species:
UniProtKB ID:
Gene ID:
  • Human(91662) Summary: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
  • Mouse(378425) NLR family, pyrin domain containing 12
  • Rat(292541) NLR family, pyrin domain containing 12
  • cow(522018) NLR family, pyrin domain containing 12
  • Horse(100063024) NLR family, pyrin domain containing 12
  • domestic cat(101085164) NLR family, pyrin domain containing 12
  • dog(100683399) NLR family, pyrin domain containing 12
  • Domestic Rabbit(100352122) NLR family, pyrin domain containing 12
  • naked mole-rat(101724058) NLR family, pyrin domain containing 12
  • sheep(101117610) NLR family, pyrin domain containing 12

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  • siRNA

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NALP12 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-NLRP12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-NALP12 antibody produced in mouse, clone 3B5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-NALP12, (N-terminal) antibody produced in mouse, clone 4B9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nlrp12,
Species
mouse
MISSION® esiRNA, targeting human NLRP12,
Species
human