NFX1
nuclear transcription factor, X-box binding 1
Synonyms:
NFX2
Species:
Human NFX1 (4799), Mouse Nfx1 (74164), Rat Nfx1 (313166), chicken NFX1 (420796), dog NFX1 (481581), domestic cat NFX1 (101089904), cow NFX1 (515680), Horse NFX1 (100053795), naked mole-rat Nfx1 (101724132), domestic guinea pig Nfx1 (100723545)
UniProtKB ID:
Gene ID:
- Human(4799) Summary: MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(74164) nuclear transcription factor, X-box binding 1
- Rat(313166) nuclear transcription factor, X-box binding 1
- chicken(420796) nuclear transcription factor, X-box binding 1
- dog(481581) nuclear transcription factor, X-box binding 1
- domestic cat(101089904) nuclear transcription factor, X-box binding 1
- cow(515680) nuclear transcription factor, X-box binding 1
- Horse(100053795) nuclear transcription factor, X-box binding 1
- naked mole-rat(101724132) nuclear transcription factor, X-box binding 1
- domestic guinea pig(100723545) nuclear transcription factor, X-box binding 1
- sheep(101103948) nuclear transcription factor, X-box binding 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NFX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-NFX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-NFX1 antibody produced in mouse, clone 1D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot