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NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Synonyms:
NFAT1, NFATP
Species:
UniProtKB ID:
Gene ID:
  • Human(4773) Summary: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
  • Mouse(18019) nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
  • Rat(311658) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • chicken(419346) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • domestic cat(101080520) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • cow(530401) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • Horse(100052657) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • dog(485930) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • sheep(101119239) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • domestic guinea pig(100722868) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • naked mole-rat(101722005) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-NFAT1 (pSer54) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse
Application
western blot
Monoclonal Anti-NFATC2, (C-terminal) antibody produced in mouse, clone 2A4, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-NFAT1 Antibody, clone 8G4.2, clone 8G4.2, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
Anti-NFAT1 Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-NFATC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
NFAT Inhibitor, >96% (HPLC), solid,
Species
mouse, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NFATC2,
Species
human
MISSION® esiRNA, targeting mouse Nfatc2,
Species
mouse