NFASC
neurofascin
NF, NRCAML
Human NFASC (23114), Mouse Nfasc (269116), Rat Nfasc (116690), naked mole-rat Nfasc (101716337), domestic guinea pig Nfasc (100721545), sheep NFASC (101109290), chicken NFASC (419824), domestic cat NFASC (101083317), cow NFASC (512796), Horse NFASC (100054575)
- Human(23114) Summary: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
- Mouse(269116) neurofascin
- Rat(116690) neurofascin
- naked mole-rat(101716337) neurofascin
- domestic guinea pig(100721545) neurofascin
- sheep(101109290) neurofascin
- chicken(419824) neurofascin
- domestic cat(101083317) neurofascin
- cow(512796) neurofascin
- Horse(100054575) neurofascin
- dog(488565) neurofascin
Custom & Knockdown Gene Products
siRNA
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Custom Gene Products
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ELISA
Antibodies
Anti-Pan-Neurofascin Antibody, clone L11A/41, clone L11A/41, from mouse,
rat
immunohistochemistry
western blot
western blot
Anti-NFASC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry