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NFASC

neurofascin

Synonyms:
NF, NRCAML
Species:
UniProtKB ID:
Gene ID:
  • Human(23114) Summary: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
  • Mouse(269116) neurofascin
  • Rat(116690) neurofascin
  • naked mole-rat(101716337) neurofascin
  • domestic guinea pig(100721545) neurofascin
  • sheep(101109290) neurofascin
  • chicken(419824) neurofascin
  • domestic cat(101083317) neurofascin
  • cow(512796) neurofascin
  • Horse(100054575) neurofascin
  • dog(488565) neurofascin

Custom & Knockdown Gene Products

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Rat Neurofascin ELISA, for serum, plasma and cell culture supernatants,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Neurofascin Antibody, common epitope, Chemicon®, from rabbit,
Species Reactivity
mouse
Application
western blot
Anti-Pan-Neurofascin Antibody, clone L11A/41, clone L11A/41, from mouse,
Species Reactivity
rat
Application
immunohistochemistry
western blot
Anti-NFASC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Nfasc,
Species
mouse
MISSION® esiRNA, targeting human NFASC,
Species
human