NF2
neurofibromin 2 (merlin)
Synonyms:
ACN, BANF, SCH
Species:
Human NF2 (4771), Mouse Nf2 (18016), Rat Nf2 (25744), chicken NF2 (395158), dog NF2 (477535), domestic cat NF2 (101087787), cow NF2 (540479), Horse NF2 (100058977), Domestic Rabbit NF2 (100357691), naked mole-rat Nf2 (101706100) ...More
UniProtKB ID:
Gene ID:
- Human(4771) Summary: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]
- Mouse(18016) neurofibromatosis 2
- Rat(25744) neurofibromin 2 (merlin)
- chicken(395158) neurofibromin 2 (bilateral acoustic neuroma)
- dog(477535) neurofibromin 2 (merlin)
- domestic cat(101087787) neurofibromin 2 (merlin)
- cow(540479) neurofibromin 2 (merlin)
- Horse(100058977) neurofibromin 2 (merlin)
- Domestic Rabbit(100357691) neurofibromin 2 (merlin)
- naked mole-rat(101706100) neurofibromin 2 (merlin)
- domestic guinea pig(100715365) neurofibromin 2 (merlin)
- sheep(101107995) neurofibromin 2 (merlin)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NF2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-phospho-Merlin (pSer10) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti- NF2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-NF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
ANTI-MERLIN(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species