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Merck

NEFL

neurofilament, light polypeptide

Sinonimi:
CMT1F, CMT2E, NF-L, NF68, NFL
Specie:
ID UniProtKB:
ID gene:
  • Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Mouse(18039) neurofilament, light polypeptide
  • Rat(83613) neurofilament, light polypeptide
  • chicken(419528) neurofilament, light polypeptide
  • cow(281348) neurofilament, light polypeptide
  • domestic cat(101081039) neurofilament, light polypeptide
  • dog(477378) neurofilament, light polypeptide
  • naked mole-rat(101704332) neurofilament, light polypeptide
  • domestic guinea pig(100731797) neurofilament, light polypeptide
  • sheep(101119539) neurofilament, light polypeptide

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Neurofilament (2F11) Mouse Monoclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
Anticorpo anti-neurofilamento L, serum, Chemicon®,
Reattività con
bovine, canine, feline, human, mouse, pig, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Reattività con
chicken, human, pig, rat
Applicazione
immunohistochemistry
microarray

western blot
Anticorpo anti-neurofilamento di 70 kDa, clone DA2, culture supernatant, clone DA2, Chemicon®,
Reattività con
bovine, human, mouse, pig, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Neurofilament Antibodies Investigator Antibody Mini-Pack, anti-neurofilament H&M antibody, anti-neurofilament H antibody, and anti-neurofilament L antibody,
Reattività con
Applicazione

Proteins

N° Catalogo
Descrizione
Specie
Neurofilament 70 kDa, porcine, ,
Specie

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human NEFL,
Specie
human