NEFL
neurofilament, light polypeptide
Synonyms:
CMT1F, CMT2E, NF-L, NF68, NFL
Species:
Human NEFL (4747), Mouse Nefl (18039), Rat Nefl (83613), chicken NEFL (419528), cow NEFL (281348), domestic cat NEFL (101081039), dog NEFL (477378), naked mole-rat Nefl (101704332), domestic guinea pig Nefl (100731797), sheep NEFL (101119539)
UniProtKB ID:
Gene ID:
- Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- Mouse(18039) neurofilament, light polypeptide
- Rat(83613) neurofilament, light polypeptide
- chicken(419528) neurofilament, light polypeptide
- cow(281348) neurofilament, light polypeptide
- domestic cat(101081039) neurofilament, light polypeptide
- dog(477378) neurofilament, light polypeptide
- naked mole-rat(101704332) neurofilament, light polypeptide
- domestic guinea pig(100731797) neurofilament, light polypeptide
- sheep(101119539) neurofilament, light polypeptide
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Neurofilament 70 kDa Antibody, clone DA2, culture supernatant, clone DA2, Chemicon®,
Species Reactivity
bovine, human, mouse, pig, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-NFL (Ser473) Antibody, clone 4F8, clone 4F8, from mouse,
Species Reactivity
bovine, human, mouse, porcine, rat, rhesus macaque
Application
immunohistochemistry
western blot
western blot
Anti-NEFL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Neurofilament-l antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM280, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-NEFL antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4729, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species