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Merck

NDUFS2

NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

Sinónimos:
CI-49
Especie:
ID UniProtKB:
ID del gen:
  • Human(4720) Summary: The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(226646) NADH dehydrogenase (ubiquinone) Fe-S protein 2
  • Rat(289218) NADH dehydrogenase (ubiquinone) Fe-S protein 2
  • domestic guinea pig(100713270) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • naked mole-rat(101701670) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • sheep(101104108) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • Zebrafish(553672) NADH dehydrogenase (ubiquinone) Fe-S protein 2
  • chicken(100857596) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • dog(478981) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • cow(327697) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
  • domestic cat(101088298) NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)

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Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Metformina hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
1,1-Dimetilbiguanida hydrochloride, 97%,
Especie
human
1,1-Dimetilbiguanida hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
1,1-Dimetilbiguanida hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
1,1-Dimetilbiguanida hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NDUFS2,
Especie
human
MISSION® esiRNA, targeting mouse Ndufs2,
Especie
mouse