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MSH2

mutS homolog 2

Synonyms:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Species:
UniProtKB ID:
Gene ID:
  • Human(4436) Summary: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(17685) mutS homolog 2 (E. coli)
  • Rat(81709) mutS homolog 2 (E. coli)
  • Zebrafish(406845) mutS homolog 2 (E. coli)
  • chicken(378799) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • dog(494002) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • domestic cat(101082051) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • Thale Cress(821383) DNA mismatch repair protein Msh2
  • cow(533115) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • naked mole-rat(101706924) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • domestic guinea pig(100724489) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
  • sheep(101107944) mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MSH2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM375, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MSH2 (Ab-1) Mouse mAb (GB12), liquid, clone GB12, Calbiochem®,
Species Reactivity
human
Application
Anti-MSH2 antibody, Rabbit monoclonal, clone SP46, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
bovine, chicken, dog, human, mouse, pig, rat
Application
flow cytometry
immunohistochemistry
Rabbit anti-MSH2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
Monoclonal Anti-Msh2 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13724, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MSH2,
Species
human