MS4A2
membrane-spanning 4-domains, subfamily A, member 2
Synonyms:
APY, ATOPY, FCER1B, FCERI, IGEL, IGER, IGHER, MS4A1
Species:
Human MS4A2 (2206), Mouse Ms4a2 (14126), Rat Ms4a2 (25316), sheep MS4A2 (443203), domestic guinea pig Ms4a2 (100715296), naked mole-rat Ms4a2 (101703025), dog MS4A2 (403799), domestic cat MS4A2 (101101505), Horse MS4A2 (100033954), cow MS4A2 (531987)
UniProtKB ID:
Gene ID:
- Human(2206) Summary: The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012]
- Mouse(14126) membrane-spanning 4-domains, subfamily A, member 2
- Rat(25316) membrane-spanning 4-domains, subfamily A, member 2
- sheep(443203) membrane-spanning 4-domains, subfamily A, member 2
- domestic guinea pig(100715296) membrane-spanning 4-domains, subfamily A, member 2
- naked mole-rat(101703025) membrane-spanning 4-domains, subfamily A, member 2
- dog(403799) membrane-spanning 4-domains, subfamily A, member 2
- domestic cat(101101505) membrane-spanning 4-domains, subfamily A, member 2
- Horse(100033954) membrane-spanning 4-domains, subfamily A, member 2
- cow(531987) membrane-spanning 4-domains, subfamily A, member 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MS4A2 antibody produced in mouse, clone 3B1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-MS4A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MS4A2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
esiRNA
Product Number
Description
Species