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MMP15

matrix metallopeptidase 15 (membrane-inserted)

Synonyms:
MT2-MMP, MTMMP2, SMCP-2
Species:
UniProtKB ID:
Gene ID:
  • Human(4324) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008]
  • Mouse(17388) matrix metallopeptidase 15
  • Rat(291848) matrix metallopeptidase 15
  • chicken(415629) matrix metallopeptidase 15 (membrane-inserted)
  • domestic cat(101088040) matrix metallopeptidase 15 (membrane-inserted)
  • cow(282887) matrix metallopeptidase 15 (membrane-inserted)
  • Horse(100062872) matrix metallopeptidase 15 (membrane-inserted)
  • dog(487257) matrix metallopeptidase 15 (membrane-inserted)
  • sheep(101122213) matrix metallopeptidase 15 (membrane-inserted)
  • domestic guinea pig(100720154) matrix metallopeptidase 15 (membrane-inserted)
  • Domestic Rabbit(100347975) matrix metallopeptidase 15 (membrane-inserted)
  • naked mole-rat(101718286) matrix metallopeptidase 15 (membrane-inserted)

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MMP15 (Cleaved-Tyr132) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
Anti-MMP15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MMP-15 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
CP-101537, ≥98% (HPLC),
Species
human, rat, mouse
CP-471474, ≥98% (HPLC),
Species
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Species
human, rat, mouse
Marimastat, ≥98% (HPLC),
Species
human, rat, mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mmp15,
Species
mouse
MISSION® esiRNA, targeting human MMP15,
Species
human