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MMP11

matrix metallopeptidase 11 (stromelysin 3)

Synonyms:
SL-3, ST3, STMY3
Species:
UniProtKB ID:
Gene ID:
  • Human(4320) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
  • Mouse(17385) matrix metallopeptidase 11
  • Rat(25481) matrix metallopeptidase 11
  • sheep(101110364) matrix metallopeptidase 11 (stromelysin 3)
  • domestic guinea pig(100713229) matrix metallopeptidase 11 (stromelysin 3)
  • naked mole-rat(101699533) matrix metallopeptidase 11 (stromelysin 3)
  • chicken(769489) matrix metallopeptidase 11 (stromelysin 3)
  • dog(486408) matrix metallopeptidase 11 (stromelysin 3)
  • Horse(100056568) matrix metallopeptidase 11 (stromelysin 3)
  • cow(539109) matrix metallopeptidase 11 (stromelysin 3)
  • domestic cat(101089148) matrix metallopeptidase 11 (stromelysin 3)

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Matrix Metalloproteinase-11, N-Terminal antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-MMP11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-MMP11 Antibody, clone 8N9D3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-Mmp11 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-MMP-11 (Stromelysin-3) Antibody, clone 5ST-4A9, clone 5ST-4A9, from mouse,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

Product Number
Description
Species
PD166793 hydrate, ≥98% (HPLC),
Species
human, rat, mouse
CP-101537, ≥98% (HPLC),
Species
human, rat, mouse
CP-471474, ≥98% (HPLC),
Species
human, rat, mouse
Marimastat, ≥98% (HPLC),
Species
human, rat, mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Mmp11,
Species
mouse
MISSION® esiRNA, targeting human MMP11, AP000349.2,
Species
human