MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
Synonyms:
3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MK-3
Species:
Human MAPKAPK3 (7867), Mouse Mapkapk3 (102626), Rat Mapkapk3 (315994), Zebrafish mapkapk3 (790934), chicken MAPKAPK3 (415917), dog MAPKAPK3 (484756), cow MAPKAPK3 (615215), domestic cat MAPKAPK3 (101096794), sheep MAPKAPK3 (101118996), domestic guinea pig Mapkapk3 (100719631) ...More
UniProtKB ID:
Gene ID:
- Human(7867) Summary: This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
- Mouse(102626) mitogen-activated protein kinase-activated protein kinase 3
- Rat(315994) mitogen-activated protein kinase-activated protein kinase 3
- Zebrafish(790934) mitogen-activated protein kinase-activated protein kinase 3
- chicken(415917) mitogen-activated protein kinase-activated protein kinase 3
- dog(484756) mitogen-activated protein kinase-activated protein kinase 3
- cow(615215) mitogen-activated protein kinase-activated protein kinase 3
- domestic cat(101096794) mitogen-activated protein kinase-activated protein kinase 3
- sheep(101118996) mitogen-activated protein kinase-activated protein kinase 3
- domestic guinea pig(100719631) mitogen-activated protein kinase-activated protein kinase 3
- Domestic Rabbit(100342292) mitogen-activated protein kinase-activated protein kinase 3
- naked mole-rat(101717099) mitogen-activated protein kinase-activated protein kinase 3
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Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-MAPKAPK3 antibody produced in mouse, clone 1C3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
ANTI-MAPKAPK3 antibody produced in mouse, clone 4B11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-MAPKAPK3 antibody produced in mouse, clone 3F4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-MAPKAPK3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Proteins
Product Number
Description
Species
MAPKAPK3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
MAPKAP Kinase 3 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human MAPKAP Kinase 3, amino acids 2-end. Activated using SAPK2a (Catalog #14-587). For use in Kinase Assays.,
Species
human
esiRNA
Product Number
Description
Species