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MAP3K6

mitogen-activated protein kinase kinase kinase 6

Synonyms:
ASK2, MAPKKK6, MEKK6
Species:
UniProtKB ID:
Gene ID:
  • Human(9064) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded kinase was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase. This kinase was found to weakly activate MAPK7, but not MAPK1/ERK or MAPK14. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(53608) mitogen-activated protein kinase kinase kinase 6
  • Rat(313022) mitogen-activated protein kinase kinase kinase 6
  • chicken(100858193) mitogen-activated protein kinase kinase kinase 6
  • cow(614598) mitogen-activated protein kinase kinase kinase 6
  • Horse(100070933) mitogen-activated protein kinase kinase kinase 6
  • domestic cat(101081315) mitogen-activated protein kinase kinase kinase 6
  • dog(487345) mitogen-activated protein kinase kinase kinase 6
  • sheep(101113737) mitogen-activated protein kinase kinase kinase 6
  • domestic guinea pig(100724385) mitogen-activated protein kinase kinase kinase 6
  • naked mole-rat(101697616) mitogen-activated protein kinase kinase kinase 6
  • Domestic Rabbit(100343069) mitogen-activated protein kinase kinase kinase 6

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MAP3K6 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-MAP3K6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
Anti-MAP3K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
ANTI-MOUSE MAP3K6 (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot

Proteins

Product Number
Description
Species
MEKK6, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAP3K6,
Species
human
MISSION® esiRNA, targeting mouse Map3k6,
Species
mouse