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MAP3K14

mitogen-activated protein kinase kinase kinase 14

Synonyms:
FTDCR1B, HS, HSNIK, NIK
Species:
UniProtKB ID:
Gene ID:
  • Human(9020) Summary: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]
  • Mouse(53859) mitogen-activated protein kinase kinase kinase 14
  • Rat(360640) mitogen-activated protein kinase kinase kinase 14
  • chicken(419964) mitogen-activated protein kinase kinase kinase 14
  • domestic cat(101083468) mitogen-activated protein kinase kinase kinase 14
  • Horse(100050140) mitogen-activated protein kinase kinase kinase 14
  • cow(508367) mitogen-activated protein kinase kinase kinase 14
  • dog(490926) mitogen-activated protein kinase kinase kinase 14
  • Domestic Rabbit(100351032) mitogen-activated protein kinase kinase kinase 14
  • naked mole-rat(101703313) mitogen-activated protein kinase kinase kinase 14
  • domestic guinea pig(100719582) mitogen-activated protein kinase kinase kinase 14
  • sheep(101118799) mitogen-activated protein kinase kinase kinase 14

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MAP3K14 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
proximity ligation assay

western blot
ANTI-NIK (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
Anti-MAP3K14 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit
Application
western blot
Anti-NIK Antibody, CT, Chemicon®, from rabbit,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
MAP3K14(NIK) Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MAP3K14,
Species
human
MISSION® esiRNA, targeting mouse Map3k14,
Species
mouse