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MAP3K10

mitogen-activated protein kinase kinase kinase 10

Synonyms:
MEKK10, MLK2, MST
Species:
UniProtKB ID:
Gene ID:
  • Human(4294) Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(269881) mitogen-activated protein kinase kinase kinase 10
  • Rat(308463) mitogen activated protein kinase kinase kinase 10
  • Zebrafish(560932) mitogen-activated protein kinase kinase kinase 10
  • domestic cat(101089731) mitogen-activated protein kinase kinase kinase 10
  • cow(781037) mitogen-activated protein kinase kinase kinase 10
  • Horse(100067981) mitogen-activated protein kinase kinase kinase 10
  • dog(484504) mitogen-activated protein kinase kinase kinase 10
  • Domestic Rabbit(100343621) mitogen-activated protein kinase kinase kinase 10
  • naked mole-rat(101718471) mitogen-activated protein kinase kinase kinase 10
  • domestic guinea pig(100716869) mitogen-activated protein kinase kinase kinase 10
  • sheep(101118723) mitogen-activated protein kinase kinase kinase 10

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MAP3K10 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
Anti-MAP3K10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-phospho-MLK1/2 (pThr312/266) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

Proteins

Product Number
Description
Species
MLK2 (1-446), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Map3k10,
Species
mouse
MISSION® esiRNA, targeting human MAP3K10,
Species
human