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LTA

lymphotoxin alpha

Synonyms:
LT, TNFB, TNFSF1
Species:
UniProtKB ID:
Gene ID:
  • Human(4049) Summary: The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
  • Mouse(16992) lymphotoxin A
  • Rat(25008) lymphotoxin alpha
  • sheep(101123078) lymphotoxin alpha (TNF superfamily, member 1)
  • domestic guinea pig(100722832) lymphotoxin alpha (TNF superfamily, member 1)
  • naked mole-rat(101718783) lymphotoxin alpha (TNF superfamily, member 1)
  • Domestic Rabbit(100328931) lymphotoxin alpha (TNF superfamily, member 1)
  • Zebrafish(554305) lymphotoxin alpha (TNF superfamily, member 1)
  • cow(280845) lymphotoxin alpha (TNF superfamily, member 1)
  • domestic cat(101084961) lymphotoxin alpha (TNF superfamily, member 1)
  • dog(607183) lymphotoxin alpha (TNF superfamily, member 1)

Custom & Knockdown Gene Products

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Human Tumor Necrosis Factor β ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Tumor Necrosis Factor-β Antibody, clone 9B9, clone 9B9, Chemicon®, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-LTA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Tumor Necrosis Factor-β human, TNF-β, recombinant, expressed in E. coli, powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Lta,
Species
mouse
MISSION® esiRNA, targeting human LTA,
Species
human