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LRR1

leucine rich repeat protein 1

Synonyms:
4-1BBLRR, LRR-1, PPIL5
Species:
UniProtKB ID:
Gene ID:
  • Human(122769) Summary: The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
  • Mouse(69706) leucine rich repeat protein 1
  • Rat(685860) leucine rich repeat protein 1
  • Thale Cress(831521) leucine-rich repeat protein 1
  • cow(790210) leucine rich repeat protein 1
  • domestic cat(101091630) leucine rich repeat protein 1
  • dog(490676) leucine rich repeat protein 1
  • chicken(423565) leucine rich repeat protein 1
  • sheep(101119991) leucine rich repeat protein 1
  • domestic guinea pig(100719517) leucine rich repeat protein 1
  • naked mole-rat(101708337) leucine rich repeat protein 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-PPIL5 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-LRR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-LRR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LRR1,
Species
human