LMNA
lamin A/C
Synonyms:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
Species:
Human LMNA (4000), Mouse Lmna (16905), Rat Lmna (60374), Zebrafish lmna (195815), cow LMNA (404144), Horse LMNA (100057663), domestic cat LMNA (101086199), dog LMNA (480124), chicken LMNA (415464), domestic guinea pig Lmna (100735212) ...More
UniProtKB ID:
Gene ID:
- Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
- Mouse(16905) lamin A
- Rat(60374) lamin A/C
- Zebrafish(195815) lamin A
- cow(404144) lamin A/C
- Horse(100057663) lamin A/C
- domestic cat(101086199) lamin A/C
- dog(480124) lamin A/C
- chicken(415464) lamin A/C
- domestic guinea pig(100735212) lamin A/C
- naked mole-rat(101704567) lamin A/C
- sheep(101107924) lamin A/C
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Lamin A−Atto 647N antibody produced in rabbit, 1.5-3 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
Anti-Lamin A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Lamin A (Cleaved-Asp230) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-LMNA antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Prelamin-A Antibody, clone 7G11, clone 7G11, from rat,
Species Reactivity
mouse
Application
immunofluorescence
western blot
western blot