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Merck

KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

Sinónimos:
AKR6A5, HKvbeta2, HKvbeta2.1, HKvbeta2.2, KCNA2B, KV-BETA-2
Especie:
ID UniProtKB:
ID del gen:
  • Human(8514) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010]
  • Mouse(16498) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • Rat(29738) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • Zebrafish(797337) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • dog(489626) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • domestic cat(101089372) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • cow(541597) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • chicken(396068) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • sheep(101122538) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • Domestic Rabbit(100328600) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • domestic guinea pig(100726297) potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • naked mole-rat(101710049) potassium voltage-gated channel, shaker-related subfamily, beta member 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-KCNAB2 (AB1) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
immunohistochemistry
western blot
Anti-Potassium Channel Kvβ2 Antibody, clone K17/70, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-KCNAB2 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Kcnab2,
Especie
mouse
MISSION® esiRNA, targeting human KCNAB2,
Especie
human