ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
Synonyms:
CENP-R, CENPR, HSU37139, NRIF3, TAP20
Species:
Human ITGB3BP (23421), Mouse Itgb3bp (67733), Rat Itgb3bp (362548), chicken ITGB3BP (424689), dog ITGB3BP (609967), cow ITGB3BP (614469), domestic cat ITGB3BP (101082676), domestic guinea pig Itgb3bp (100728578), naked mole-rat Itgb3bp (101712566), sheep ITGB3BP (101108702)
UniProtKB ID:
Gene ID:
- Human(23421) Summary: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
- Mouse(67733) integrin beta 3 binding protein (beta3-endonexin)
- Rat(362548) integrin beta 3 binding protein (beta3-endonexin)
- chicken(424689) integrin beta 3 binding protein (beta3-endonexin)
- dog(609967) integrin beta 3 binding protein (beta3-endonexin)
- cow(614469) integrin beta 3 binding protein (beta3-endonexin)
- domestic cat(101082676) integrin beta 3 binding protein (beta3-endonexin)
- domestic guinea pig(100728578) integrin beta 3 binding protein (beta3-endonexin)
- naked mole-rat(101712566) integrin beta 3 binding protein (beta3-endonexin)
- sheep(101108702) integrin beta 3 binding protein (beta3-endonexin)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ITGB3BP antibody produced in mouse, clone 3F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-ITGB3BP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species