IRF4
interferon regulatory factor 4
Synonyms:
LSIRF, MUM1, NF-EM5
Species:
Human IRF4 (3662), Mouse Irf4 (16364), Rat Irf4 (291100), chicken IRF4 (374179), domestic cat IRF4 (101089438), cow IRF4 (506141), Horse IRF4 (100068881), Horse IRF4 (100049827), domestic guinea pig Irf4 (100719564), naked mole-rat Irf4 (101705637)
UniProtKB ID:
Gene ID:
- Human(3662) Summary: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
- Mouse(16364) interferon regulatory factor 4
- Rat(291100) interferon regulatory factor 4
- chicken(374179) interferon regulatory factor 4
- domestic cat(101089438) interferon regulatory factor 4
- cow(506141) interferon regulatory factor 4
- Horse(100068881) interferon regulatory factor 4
- Horse(100049827) interferon regulatory factor 4
- domestic guinea pig(100719564) interferon regulatory factor 4
- naked mole-rat(101705637) interferon regulatory factor 4
- sheep(101111234) interferon regulatory factor 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IRF-4 Antibody, clone 1E10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-MUM1/IRF4 antibody, Rabbit monoclonal, clone SP114, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
bovine, chicken, dog, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-Irf4 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14615, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-IRF4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-IRF4 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
esiRNA
Product Number
Description
Species