IL6R
interleukin 6 receptor
Synonyms:
CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species:
Human IL6R (3570), Rat Il6r (24499), Zebrafish il6r (100135755), cow IL6R (507359), domestic cat IL6R (101085689), dog IL6R (612271), domestic guinea pig Il6r (100730490), naked mole-rat Il6r (101704925), sheep IL6R (101103369)
UniProtKB ID:
Gene ID:
- Human(3570) Summary: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
- Rat(24499) interleukin 6 receptor
- Zebrafish(100135755) interleukin 6 receptor
- cow(507359) interleukin 6 receptor
- domestic cat(101085689) interleukin 6 receptor
- dog(612271) interleukin 6 receptor
- domestic guinea pig(100730490) interleukin 6 receptor
- naked mole-rat(101704925) interleukin 6 receptor
- sheep(101103369) interleukin 6 receptor
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CD126 Antibody, clone B-R6, clone B-R6, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
Anti-IL-6R Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-IL6R antibody produced in mouse, clone 2G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-IL6R antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-IL6R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
sIL-6 Receptor alpha human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
esiRNA
Product Number
Description
Species