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IL6R

interleukin 6 receptor

Synonyms:
CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80
Species:
Human IL6R (3570), Rat Il6r (24499), Zebrafish il6r (100135755), cow IL6R (507359), domestic cat IL6R (101085689), dog IL6R (612271), domestic guinea pig Il6r (100730490), naked mole-rat Il6r (101704925), sheep IL6R (101103369)
UniProtKB ID:
P08887, A8KAE8, B2R6V4, Q16202, Q53EQ7, Q5FWG2, Q5VZ23
Gene ID:
  • Human(3570) Summary: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
  • Rat(24499) interleukin 6 receptor
  • Zebrafish(100135755) interleukin 6 receptor
  • cow(507359) interleukin 6 receptor
  • domestic cat(101085689) interleukin 6 receptor
  • dog(612271) interleukin 6 receptor
  • domestic guinea pig(100730490) interleukin 6 receptor
  • naked mole-rat(101704925) interleukin 6 receptor
  • sheep(101103369) interleukin 6 receptor

Custom & Knockdown Gene Products

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
CBL714
Anti-CD126 Antibody, clone B-R6, clone B-R6, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
WH0003570M1
Monoclonal Anti-IL6R antibody produced in mouse, clone 2G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB1403972
Monoclonal Anti-IL6R antibody produced in mouse, clone 1E11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB1410708
Anti-IL6R antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
ZRB2953
Anti-IL-6R Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP3097
sIL-6 Receptor alpha human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
EHU140561
MISSION® esiRNA, targeting human IL6R,
Species
human