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IL5RA

interleukin 5 receptor, alpha

Synonyms:
CD125, CDw125, HSIL5R3, IL5R
Species:
UniProtKB ID:
Gene ID:
  • Human(3568) Summary: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
  • Mouse(16192) interleukin 5 receptor, alpha
  • Rat(114103) interleukin 5 receptor, alpha
  • chicken(771801) interleukin 5 receptor, alpha
  • domestic cat(101099031) interleukin 5 receptor, alpha
  • cow(615848) interleukin 5 receptor, alpha
  • dog(476553) interleukin 5 receptor, alpha
  • domestic guinea pig(100379257) interleukin 5 receptor, alpha
  • naked mole-rat(101701153) interleukin 5 receptor, alpha
  • sheep(101111837) interleukin 5 receptor, alpha

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Human IL-5 R α ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL5RA antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL5RA,
Species
human