IL2RB
interleukin 2 receptor, beta
Synonyms:
CD122, IL15RB, P70-75
Species:
Human IL2RB (3560), Mouse Il2rb (16185), Rat Il2rb (25746), domestic guinea pig Il2rb (100730639), naked mole-rat Il2rb (101726369), sheep IL2RB (101107088), Zebrafish il2rb (793920), dog IL2RB (403439), domestic cat IL2RB (101092622)
UniProtKB ID:
Gene ID:
- Human(3560) Summary: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]
- Mouse(16185) interleukin 2 receptor, beta chain
- Rat(25746) interleukin 2 receptor, beta
- domestic guinea pig(100730639) interleukin 2 receptor, beta
- naked mole-rat(101726369) interleukin 2 receptor, beta
- sheep(101107088) interleukin 2 receptor, beta
- Zebrafish(793920) interleukin 2 receptor, beta
- dog(403439) interleukin 2 receptor, beta
- domestic cat(101092622) interleukin 2 receptor, beta
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IL2RB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot
western blot
Monoclonal Anti-CD122 antibody produced in mouse, clone TU27,
Species Reactivity
human
Application
flow cytometry
Anti-phospho-IL-2R β (pTyr364) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-phospho-IL-2Rβ/CD122 (pTyr364) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Anti-IL2RB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry