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Merck

IL1RN

interleukin 1 receptor antagonist

Synonyms:
DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4
Species:
UniProtKB ID:
Gene ID:
  • Human(3557) Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(16181) interleukin 1 receptor antagonist
  • Rat(60582) interleukin 1 receptor antagonist
  • domestic guinea pig(100721865) interleukin 1 receptor antagonist
  • naked mole-rat(101706342) interleukin 1 receptor antagonist
  • sheep(780505) interleukin 1 receptor antagonist
  • Domestic Rabbit(100301539) interleukin 1 receptor antagonist
  • chicken(100861585) interleukin 1 receptor antagonist
  • cow(281860) interleukin 1 receptor antagonist
  • Horse(100034236) interleukin 1 receptor antagonist
  • dog(403660) interleukin 1 receptor antagonist
  • domestic cat(101096719) interleukin 1 receptor antagonist

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ELISA

Product Number
Description
Species
Equine Interleukin-1 Receptor Antagonist / IL-1F3 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
horse