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IL17RC

interleukin 17 receptor C

Synonyms:
IL17-RL, IL17RL
Species:
UniProtKB ID:
Gene ID:
  • Human(84818) Summary: This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]
  • Mouse(171095) interleukin 17 receptor C
  • Rat(297520) interleukin 17 receptor C
  • domestic cat(101092091) interleukin 17 receptor C
  • cow(504855) interleukin 17 receptor C
  • Horse(100058271) interleukin 17 receptor C
  • dog(610118) interleukin 17 receptor C
  • domestic guinea pig(100730048) interleukin 17 receptor C
  • naked mole-rat(101701402) interleukin 17 receptor C
  • sheep(101123416) interleukin 17 receptor C
  • Domestic Rabbit(100350539) interleukin 17 receptor C

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Human IL-17 RC ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL17RC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-IL17RC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL17RC,
Species
human