IKZF3
IKAROS family zinc finger 3 (Aiolos)
Synonyms:
AIO, AIOLOS, ZNFN1A3
Species:
Human IKZF3 (22806), Mouse Ikzf3 (22780), Rat Ikzf3 (303511), chicken IKZF3 (395614), domestic cat IKZF3 (101092807), cow IKZF3 (540676), dog IKZF3 (491020), sheep IKZF3 (101104255), domestic guinea pig Ikzf3 (100727931), naked mole-rat Ikzf3 (101703429)
UniProtKB ID:
Gene ID:
- Human(22806) Summary: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
- Mouse(22780) IKAROS family zinc finger 3
- Rat(303511) IKAROS family zinc finger 3
- chicken(395614) IKAROS family zinc finger 3 (Aiolos)
- domestic cat(101092807) IKAROS family zinc finger 3 (Aiolos)
- cow(540676) IKAROS family zinc finger 3 (Aiolos)
- dog(491020) IKAROS family zinc finger 3 (Aiolos)
- sheep(101104255) IKAROS family zinc finger 3 (Aiolos)
- domestic guinea pig(100727931) IKAROS family zinc finger 3 (Aiolos)
- naked mole-rat(101703429) IKAROS family zinc finger 3 (Aiolos)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IKFZ3 degron tag Antibody, clone 1C3-D3-F8, ,
Species Reactivity
bovine, human, monkey, rat
Application
western blot
Anti-Aiolos Antibody, clone 9D10, clone 9D10, from mouse,
Species Reactivity
human, mouse
Application
ChIP
western blot
western blot
Anti-IKZF3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-IKZF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-IKZF3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot