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IFNL2

interferon, lambda 2

Synonyms:
IL-28A, IL28A
Species:
Human IFNL2 (282616), Mouse Ifnl2 (330496), naked mole-rat Ifnl2 (101699159)
UniProtKB ID:
Q8IZJ0, Q6VN55, Q8IWL7
Gene ID:
  • Human(282616) Summary: This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
  • Mouse(330496) interferon lambda 2
  • naked mole-rat(101699159) interferon, lambda 2

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