HEY2
hairy/enhancer-of-split related with YRPW motif 2
Synonyms:
CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32
Species:
Human HEY2 (23493), Mouse Hey2 (15214), Rat Hey2 (155430), sheep HEY2 (100271925), domestic guinea pig Hey2 (100727826), naked mole-rat Hey2 (101716129), Zebrafish hey2 (58146), dog HEY2 (484115), cow HEY2 (538619), domestic cat HEY2 (101083681)
UniProtKB ID:
Gene ID:
- Human(23493) Summary: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(15214) hairy/enhancer-of-split related with YRPW motif 2
- Rat(155430) hairy/enhancer-of-split related with YRPW motif 2
- sheep(100271925) hairy/enhancer-of-split related with YRPW motif 2
- domestic guinea pig(100727826) hairy/enhancer-of-split related with YRPW motif 2
- naked mole-rat(101716129) hairy/enhancer-of-split related with YRPW motif 2
- Zebrafish(58146) hairy/enhancer-of-split related with YRPW motif 2
- dog(484115) hairy/enhancer-of-split related with YRPW motif 2
- cow(538619) hairy/enhancer-of-split related with YRPW motif 2
- domestic cat(101083681) hairy/enhancer-of-split related with YRPW motif 2
- chicken(421718) hairy/enhancer-of-split related with YRPW motif 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HEY2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-HEY2, (N-terminal) antibody produced in mouse, clone 2B10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-HEY2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-HEY2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human
Application
western blot
Anti-Hey 2/HRT2 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
immunohistochemistry