HDAC3
histone deacetylase 3
Synonyms:
HD3, RPD3, RPD3-2
Species:
Human HDAC3 (8841), Mouse Hdac3 (15183), Rat Hdac3 (84578), sheep HDAC3 (101107092), domestic guinea pig Hdac3 (100718985), naked mole-rat Hdac3 (101708680), Zebrafish hdac3 (393965), cow HDAC3 (404125), domestic cat HDAC3 (101100941), dog HDAC3 (478040) ...More
UniProtKB ID:
Gene ID:
- Human(8841) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Mouse(15183) histone deacetylase 3
- Rat(84578) histone deacetylase 3
- sheep(101107092) histone deacetylase 3
- domestic guinea pig(100718985) histone deacetylase 3
- naked mole-rat(101708680) histone deacetylase 3
- Zebrafish(393965) histone deacetylase 3
- cow(404125) histone deacetylase 3
- domestic cat(101100941) histone deacetylase 3
- dog(478040) histone deacetylase 3
- chicken(395506) histone deacetylase 3
- fruit fly(44446) Histone deacetylase 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HDAC3 Antibody, clone 1M1O7, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-HDAC3 Antibody, clone 3G6, clone 3G6, Upstate®, from mouse,
Species Reactivity
bovine, hamster, human, mouse
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-HDAC3 Antibody, clone 1H19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-HDAC3 Rabbit Monoclonal Antibody, clone RM439, affinity purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-HDAC3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species