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HAX1

HCLS1 associated protein X-1

Synonyms:
HCLSBP1, HS1BP1, SCN3
Species:
UniProtKB ID:
Gene ID:
  • Human(10456) Summary: The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(23897) HCLS1 associated X-1
  • Rat(291202) HCLS1 associated protein X-1
  • domestic guinea pig(100731401) HCLS1 associated protein X-1
  • naked mole-rat(101726528) HCLS1 associated protein X-1
  • sheep(101111760) HCLS1 associated protein X-1
  • Zebrafish(436609) HCLS1 associated protein X-1
  • cow(506895) HCLS1 associated protein X-1
  • domestic cat(101097787) HCLS1 associated protein X-1
  • dog(480134) HCLS1 associated protein X-1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Hax1b antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-HAX-1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot
Monoclonal Anti-Hax1a antibody produced in mouse, clone 9G3D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
western blot
Monoclonal Anti-Hax1a antibody produced in mouse, clone 9G6C6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
western blot
Monoclonal Anti-Hax1a antibody produced in mouse, clone 8F9G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Hax1,
Species
mouse
MISSION® esiRNA, targeting human HAX1,
Species
human