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Merck

GUCY2D

guanylate cyclase 2D, membrane (retina-specific)

Synonyms:
CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC
Species:
UniProtKB ID:
Gene ID:
  • Human(3000) Summary: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]
  • Mouse(14918) guanylate cyclase 2d
  • Rat(113911) guanylate cyclase 2d
  • dog(403863) guanylate cyclase 2D, membrane (retina-specific)
  • cow(282245) guanylate cyclase 2D, membrane (retina-specific)
  • sheep(101120932) guanylate cyclase 2D, membrane (retina-specific)

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Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-GUCY2D antibody produced in mouse, clone 7E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
ANTI-GUCY2D antibody produced in mouse, clone 5E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-GUCY2D antibody produced in mouse, clone 6E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-GUCY2D antibody produced in mouse, clone 6D9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-RetGC-1/GUCY2D Antibody, clone 6D8.2, clone 6D8.2, from mouse,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Gucy2d,
Species
mouse