Accéder au contenu
Merck

GSTA4

glutathione S-transferase alpha 4

Synonymes:
GSTA4-4, GTA4
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(2941) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis. [provided by RefSeq, Jul 2008]
  • Mouse(14860) glutathione S-transferase, alpha 4
  • Rat(300850) glutathione S-transferase alpha 4
  • domestic guinea pig(100732190) glutathione S-transferase alpha 4
  • naked mole-rat(101714626) glutathione S-transferase alpha 4
  • cow(533917) glutathione S-transferase alpha 4
  • Horse(100056597) glutathione S-transferase alpha 4
  • dog(474939) glutathione S-transferase alpha 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Activity Assay

Référence du produit
Description
Espèce(s)
Glutathione Assay Kit, Fluorimetric, sufficient for 200 multiwell tests,
Espèce(s)
human
Glutathione-S-Transferase (GST) Assay Kit, sufficient for 500 multiwell tests,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-GSTA4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human, mouse
Application
western blot
Anti-GSTA4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot

Cell Lines

Référence du produit
Description
Espèce(s)
GST A4-4, Recombinant Human, ,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Gsta4,
Espèce(s)
mouse
MISSION® esiRNA, targeting human GSTA4,
Espèce(s)
human