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GRP

gastrin-releasing peptide

Synonyms:
BN, GRP-10, preproGRP, proGRP
Species:
UniProtKB ID:
Gene ID:
  • Human(2922) Summary: This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(225642) gastrin releasing peptide
  • Rat(171101) gastrin releasing peptide
  • Zebrafish(559978) gastrin-releasing peptide
  • cow(615323) gastrin-releasing peptide
  • Horse(100050124) gastrin-releasing peptide
  • dog(610154) gastrin-releasing peptide
  • chicken(425213) gastrin-releasing peptide
  • fruit fly(34993) grapes
  • fruit fly(39824) Gag related protein
  • sheep(443332) gastrin-releasing peptide
  • domestic guinea pig(100728828) gastrin-releasing peptide
  • naked mole-rat(101722365) gastrin-releasing peptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GRP antibody produced in mouse, clone 3A11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

Proteins

Product Number
Description
Species
[Tyr4]-Bombesin, ≥97% (HPLC),
Species
human
Gastrin Releasing Peptide human, ≥97% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GRP,
Species
human